JohnMu from Google posted a blog post named Working with multi-regional websites. The post goes over many of the SEO implications behind making multiple web sites all targeting different regions around the world.
John discusses URL structures, hosting, domains, using Webmaster Tools and much more. If you ever had to deal with a multi-regional web site before, this post is something you should read. It does not however fully cover multi-lingual issues, but a post on that is coming soon.
The beauty of this post is that it is living over in the Google Webmaster Help forums. John is there answering additional questions that were either confusing or not clear to readers. So if you have additional questions, hit up the forums.
Forum discussion at Google Webmaster Help and WebmasterWorld.

Comments:
Mohannad
10/16/2010 01:23 am
Hi, This Mohannad, I'm marketing manager of the company that owns eutschegulf.com domain, I need to know the weaknesses that cause do not see the site in search engines as well as to gain the largest possible number of visitors. How can you help me with your price please? Regards