A thread over at Cre8asite Forums discusses a recent Class Action Lawsuit brought against a large retailer, complaining the site is "gibberish" to blind users. Some good points made about accessibility and the responsibility especially of large sites to ensure that their pages can be understood by disability software such as screen readers.
I found an old post by Ben from 2004 bringing up some very valid points on this issue, and it seems sad that his wishes for greater accessibility have yet to be fully adopted. Read his post: Web Accessibility Required By Law in UK - Hard Pressed to Catch On With Mainstream
See the current thread at Cre8asite Forums