Shortly after Google announced the Caffeine preview update The Register published an article named Google File System II. The two are actually mostly unrelated, in that the caffeine update runs off the second Google File System, like Microsoft Word runs off Windows.
But Matt Cutts confirmed in a recent interview with The Register that Google's Caffeine infrastructure, does indeed run off the second Google File System. The article said, "Matt Cutts confirms that the company's new Caffeine search infrastructure is built atop a complete overhaul of the company's custom-built Google File System."
"There are a lot of technologies that are under the hood within Caffeine, and one of the things that Caffeine relies on is next-generation storage," he says. "Caffeine certainly does make use of the so-called GFS2."
How does this impact SEOs? Well, honestly, it doesn't. Caffeine will have an impact, but it running on GFSII really doesn't matter technically to SEOs.
Forum discussion at WebmasterWorld.